516th

516th may refer to:


 * 516th Aeronautical Systems Wing, wing of the United States Air Force assigned to Wright-Patterson Air Force Base, Ohio
 * 516th Air Defense Group, disbanded United States Air Force organization
 * 516th Infantry Regiment (United States) ("Bastogne Bulldogs"), a gliderborne regiment of the U.S. 101st Airborne Division
 * 516th Signal Brigade (United States), forward based major subordinate operations and maintenance command of the 311th Signal Command
 * 516th Strategic Fighter Squadron, inactive United States Air Force unit