German submarine U-253

German submarine U-253 was a Type VIIC U-boat built for the Nazi German Kriegsmarine for service during World War II.

The U-boat was laid down 15 November 1940 at the Bremer Vulkan yard in Bremen-Vegesack, launched on 30 August 1941 and commissioned on 21 October 1941. U-253 served with the 8th U-boat Flotilla for training and later served operationally with the 6th U-boat Flotilla from 1 to 25 September 1942. U-253 completed one patrol but did not sink any ships.

U-253 was sunk with all hands on 25 September 1942 in the Denmark Strait, northwest of Iceland, at 66.99997°N, -23°W. The cause of U-253's loss is not clear, but believed to be a British mine.