German submarine U-50

U-50 may refer to one of the following German submarines:


 * SMU U-50, a Type U 43 submarine launched in 1915 and that served in the First World War until sunk on or after 31 August 1917
 * During the First World War, Germany also had these submarines with similar names:
 * SMU UB-50, a Type UB III submarine launched in 1917 and surrendered 16 January 1919; broken up at Swansea in 1922
 * SMU UC-50, a Type UC II submarine launched in 1916 and went missing after 7 January 1918


 * GS U-50 (1939), a Type VIIB submarine that served in the Second World War until sunk on 6 April 1940

U50 may also refer to the General Electric U50, a class of diesel electric locomotive.