388th

388th may refer to:


 * 388th Electronic Combat Squadron, inactive United States Air Force unit
 * 388th Fighter Squadron or 132nd Fighter Wing (132d W), United States Air Force unit assigned to the Iowa Air National Guard, located at Des Moines International Airport, Iowa
 * 388th Fighter Wing, 4th Fighter Squadron (4 FS), conducts flying operations and equipment maintenance to maintain combat readiness of an 18-aircraft F-16C LANTIRN squadron
 * 388th Operations Group, the flying component of the 388th Fighter Wing, assigned to the Air Combat Command Twelfth Air Force