USS Macdonough

USS Macdonough may refer to:


 * USS Macdonough (DD-9), was an early destroyer, launched in 1900 and served until 1919


 * USS Macdonough (DD-331), was a Clemson-class destroyer, launched in 1920 and served until 1930


 * USS Macdonough (DD-351), was a Farragut-class destroyer, launched in 1934 and served through World War II until 1945


 * USS Macdonough (DDG-39), was a Farragut-class guided missile frigate (destroyer leader), launched in 1959 and served until 1992


 * SS Thomas Macdonough a Liberty ship