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| Systematic (IUPAC) name | |
|---|---|
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1-azabicyclo[2.2.2]octan-8-yl 2-cyclopentyl-2-hydroxy-2-phenylethanoate | |
| Identifiers | |
| CAS Number |
26758-53-2  |
| PubChem | CID 33597 |
| Chemical data | |
| Formula | C20H29NO3 |
| Molar mass | 329.433 g/mol |
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SMILES
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EA-3167 is a potent and long lasting anticholinergic deliriant drug, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, in an attempt to develop non-lethal incapacitating agents. EA-3167 has identical effects to QNB, but is even more potent and longer lasting, with an effective dose when administered by injection of as little as 2.5μg/kg (i.e. 0.2 milligrams for an 80 kg person), and a duration of 120–240 hours (5–10 days).[1][2] However unlike QNB, EA-3167 was never weaponized or manufactured in bulk.
See also[]
- N-methyl-3-piperidyl benzilate
- N-ethyl-3-piperidyl benzilate
- 3-Quinuclidinyl benzilate
- Ditran
References[]
- ↑ Wills H (1982). "Appendix I: Digest Report -- Anticholinergic Chemicals". In National Research Council (U.S.). Committee on Toxicology. Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents. 1. Washington, D.C.: National Academies Press. pp. 195–196. OCLC 35472774. http://www.nap.edu/openbook.php?record_id=740&page=195.
- ↑ Ketchum JS (2006). Chemical Warfare Secrets Almost Forgotton. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks. ISBN 978-1-4243-0080-8.
The original article can be found at EA-3167 and the edit history here.